You need to fold this preflop; this is a good spot to explain the "gap theory"; basically you need a tighter calling range than what they're opening with, the differences in ranges, the "gap", is dependent upon how many people that are left to act, and skill differences.
Although technically speaking, this theory isn't completely true and more applies for medium stack(which is what you are at here) tournament poker, it's still good to follow whilst you're figuring out preflop.
So let's say his range here is 99+, AA-22,AK-AJ,ATs,KQs, you only have 48% equity, which considering you could get squeezed and that you have reversed implied odds(if a lot of money goes into the pot you're most likely behind, and you can't play your hand aggressively due to rarely being able to flop a very strong hand, even AQ2 isn't a good board to get a lot of money in on) Villain's assigned preflop range is actually too lose and bad, but the majority of micro guys underestimate position and overestimate hand strength, which causes them to open too many hands from EP.
If you where on the button, this call wouldn't be terrible, as you are guaranteed to have position and the threat of being squeezed is greatly diminished, a 3bet bluff would be okay as well. However, with your skill level, just fold this, it is a tricky hand to play against a tight range and you're gonna get yourself into trouble.
If you have reads that he's a fish, than this is a great call, as your hand is no longer in "gap" territory; AQs does great against a range like this:
Fish are more likely to make mistakes postflop as well, so even making a slight mistake preflop to capitalize on greater mistakes post-flops is a good idea, but that is rather advanced and assumes you have enough skill edge to actually capitalize and not spew.
As played, you came to the flop with 4 SPR and villain is doing a random PSB for no apparent reason; therefore, he's likely spazzy and with the other premise, is likely to have a wide range, so just go all-in on the flop, you have a fair amount of pot equity and fold equity, and not risking much to gain it. You're basically committed if you call the flop anyway, and it's not as if you can fold this much equity.