I think I need to do a bit more thinking about the 1:0 and 0:1 as pat before writing any more to avoid providing terrible advice.  The 0:1 spot where we're patting OOP is especially tricky and opponent dependent.  So I've decided to write about another spot instead for the time being.

2:1 – “card ahead, come and get me”
This spot is less frequent to occur, particularly with tighter players and players who are familiar with the game.  We know drawing 2 is generally bad, especially OOP.  However, there are definitely times where we’ll consider defending 2cds (mostly shorthanded) and there will definitely be villains who do this more frequently than they should.  We’ll look at this from the 2cd and 1cd perspective.

1cd: Because we’re “card ahead” we’re more often than not going to end up with the best hand post draw.  It’s difficult to draw 2 cards to a really strong hand (7x2 will make an 8 or better like 9% of the time, and a T or better about 22% of the time if I've done my math correctly) and drawing 1 we’re more likely to hit our hand anyway.  Because our opponent misses so often, we’re going to do well to bet both strong value hands and hands with little to no showdown quite a bit of the time.  Because we anticipate our opponent to adjust to us polarizing our range (to something that likely includes more bluffs than value type hands) by calling us with a slightly wider range than normal, we can somewhat capitalize by betting for thinner value as well.  Hands that might be check backs in 1:1 or 1:0 spots can be good betting spots.  If our opponent adjusts to us doing this by check/raising or raising more frequently rather than calling we can readjust with 3b bluffs and changing the ratio of value to bluff hands in our range.  When we’re IP taking 1 card can be a profitable snow line with any 5 cards against some opponents (from time to time of course, unless our opponent is letting us get away with this constantly).

2cd: When OOP we should almost always be checking against competent Villains who are taking advantage of the above fact.  If the opponent is not capable of value betting wide then we’d do better to lead value hands and bluffs and check/calling bluff catchers and check/folding other nonshowdownable hands.  Better hands to bluff actively with include things that we might snow with or cause us to tend to snow with predraw (hitting more twos and lowcards, pairing small etc..).  Basically as the 2cd we want to be adjusting in a way that will make the 1cds life as miserable as possible.  Basically we're going to actively attempt to do everything we're attempting to guard against as the 1cd.  If we feel our opponent is betting too wide, we can adjust by bluffraising more or consider some kind of donkbetting strategy if he's tending to give us too much credit.

The two other spots I'll eventually write about will be the 1:1:1 and 1:1:0 spots.

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Last TDL session of the day +39BB in 0.5/1, +2BB at 1/2, so not a bad result :) for 80 hands.